Complete Chemical Synthesis of DNA- Thanks to Click Chemistry

Dr Ali Tavassoli, a Reader in chemical biology at the University of Southampton, along with his collaborators, Dr Jeremy Blaydes and Professor Tom Brown, has lead an interdisciplinary study that assembles DNA which is functional in human cells using click chemistry. A linker has been used to stitch DNA strands together. Human cells can still read through this DNA correctly irrespective of the fact that linker used was not found in nature. This finding has opened doors to the possibility of total chemical synthesis of DNA. Click chemistry functions like nature to generate substances quickly by joining small units together. Oligonucleotides were joined together to create artificial DNA using click chemistry. The usual approaches to assemble DNA strands comprises of  DNA synthesis, PCR amplification and enzymatic ligation. Click technique has several advantages over these usual...

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Walk in Interview for research scholars at ILS, Bhubaneswar

The Institute of Life Sciences (ILS), an autonomous institute has been brought under the fold of the Department of Biotechnology, Government of India in August 2002. The institute is located in close proximity to other research institutions at Bhubaneswar. The institute was earlier established on February 11, 1989 and was under the administrative and financial control of Department of Science and Technology, Government of Orissa. Prime minister of India dedicated the institute to the nation on July 15, 2003 with a declaration to develop the institute as a "National Centre for Excellence". Eligible and interested candidates can appear for the walk-in-interview for JRF/SRF/RA at ILS, Bhubaneswar Position title : JRF/SRF/RA Project title : “Enhancement of yield potential of rice cultivars by application of Invinsa (1-methylcyclopropene), an ethylene action inhibitor ”  Duration : Co-terminus with project but not less than six months. Fellowship : Rs.18000/- plus @ 20% HRA or as per suitability (In case of deserving candidates the fellowship may be fixed at higher level) Desired Profile : M. Sc in Botany/Life Sciences/Agriculture/ Biotechnology. Preference will be given to candidates having working experience in field based rice related project evidenced by publications in journals of international repute. Interested and eligible candidates may apply with detailed bio-data to Director, Institute of Life Sciences, Nalco Square, Bhubaneswar-23 or by email to academic@ils.res.in on or before last date. Short-listed candidates called for interview will have to submit self-attested copies of their educational qualification and experience certificates...

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JRF Post at NICED, Kolkata

The vision, of the National Institute of Cholera and Enteric Diseases (NICED), is to perform research and develop strategies for treatment, prevention and control of enteric infections and HIV/AIDS threatening the Nation’s health. The following post will be filled up on purely temporary basis under the project entitled “Anti-diarrheal mechanism of Zinc: Effect on epithelial ion transport and barrier function” under Dr. Mirajul Hoque Kazi, Ramalingaswami Fellow & P.I. of the project: Position title : JRF No of Post : One Fellowship : Rs. 16,000/- p.m. Plus 30% HRA Desired Profile : M.Sc. First Class in Life Sciences/Physiology/Biochemistry/Biotechnology with CSIR/UGC NET/DBT/ICMR JRF Qualified. Age : Below 28 years Candidates fulfilling the above criteria may report to the Administrative Officer, along with Bio-data showing academic record from Matriculation onward experience, recent passport size photograph and attested copies of relevant certificates. Address: National Institute of Cholera & Enteric Diseases (JICA Building within ID & BG Hospital Campus) P-33, C.I.T. Road, Scheme-XM, Beliaghata, Kolkata- 700 010 Deadline : 21.02.14 Source: click here! ...

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