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Sunday 19 January 2014

Tiny Synthetic Self propelled Swimming Bio-bots!

The world of aquatic micro organisms shall soon see synthetic self-propelled swimming bio-bots. A class of tiny bio-hybrid machines that can traverse the viscous fluids of biological environments on their own, has been developed by a team of engineers. Led by Taher Saif, the University of Illinois Gutgsell Professor of mechanical science and engineering, developed these tiny machines that swim like a sperm.

These bio-bots are modelled after single-celled microbes with long tails called flagella. Its body has been made from a flexible polymer. Then ,heart cells were cultured  near the junction of the head and the tail. The cells self-align and synchronize to beat together, sending a wave down the tail that propels the bio-bot forward. Such self organization is a remarkable emergent phenomenon. However, how the cells communicate with each other on the flexible polymer tail still needs to be understood. But the cells must beat together, in the right direction, for the tail to move.

According to Saif, it is a minimal amount of engineering, only a head and a wire. Then the cells come in, interact with the structure, and make it functional.
Also built two-tailed bots has been developed by the team, which they found can swim even faster. There are possibilities of navigation due to multiple tails. In future , Bots can be developed that could sense chemicals or light and navigate toward a target for medical or environmental applications. Possibility of elementary structures and seeding them with stem cells that would differentiate into smart structures to deliver drugs, perform minimally invasive surgery or target cancer is further thought of by the researchers.
The swimming bio-bot project is part of a larger National Science Foundation-supported Science and Technology Center on Emergent Behaviors in Integrated Cellular Systems, which also produced the walking bio-bots developed at Illinois in 2012.
According to A center director Roger Kamm, a professor of biological and mechanical engineering at the Massachusetts Institute of Technology, The most intriguing aspect of this work is that it demonstrates the capability to use computational modelling in conjunction with biological design to optimize performance, or design entirely different types of swimming bio-bots